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Timeline of changes: Clinical studies show that reductions in visceral fat can be observed within 36 months, along with improvements in metabolic parameters such as triglycerides and cholesterol

For CLA common trial doses are near 3.2 grams per day

(PubMed) Janniger CK, Schwartz RA, Szepietowski JC, Reich A

[27] discussed differences in effective concentrations between experimental conditions (i.e., the concentrationresponse curve to agonists shifted to the right by two or more orders of magnitude and the GLP-1 effects in the nanomolar range were within the acceptable physiological range)